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Course Catalog

Today is Monday, October 20, 2014

Course List


BE 1000 UNDERGRADUATE RESEARCH (0-0) Freshman level undergraduate research. Prerequisite: Departmental good standing and permission of instructor. May be taken a maximum of 3 times.

BE 1104 INTRODUCTION TO ENGINEERING (1-0) Introduction to basic engineering concepts. Students will become familiar with engineering and its many sub-fields, ethical responsibilites, creativity and design.

BE 1225 INTRODUCTION TO BIOENGINEERING (2-0) Topics include introduction to basic engineering principles and quantitative methods, their applications in analyzing and solving problems in biology and medicine. Also includes new trends in the development of bioengineering and biotechnology. Course includes visits to the area hospitals and bioengineering industry.

BE 2000 UNDERGRADUATE RESEARCH (0-0) Sophomore level undergraduate research. Prerequisite: Departmental good standing and permission of instructor. May be taken a maximum of 3 times.

BE 3000 UNDERGRADUATE RESEARCH (0-0) Junior level undergraduate research. Prerequisite: Departmental good standing and permission of instructor. May be taken a maximum 3 times.

BE 3310 FLUID FLOW, CELLULAR MECHANICS WITH LABORATORY (2-1) This course provides an introduction to the fundamentals of fluid mechanics with an emphasis on biological systems. Topics of boundary layers, fluid properties, and laminar and turbulent flows will be covered. Cell motility and mechanics of cell movements in blood and cellular circuits will be covered. The course will have lecture and laboratory sessions. Prerequisites: Junior Standing, BIOL 1442, PHYS 1444, CHEM 2321, CHEM 2181, and MATH 3319.

BE 3320 MEASUREMENT LABORATORY (0-3) Hands-on experiments with use of transducers used for chemical, mechanical, electrical, and thermal biomedical measurements. Computer-based means of converting analog transducer output into digital form. Analysis of experimentally collected data including error analysis, repeatability, resolution, and functional specifications. Prerequisite: BIOL 1442, CHEM 2181, CHEM 2321, MATH 3319, and PHYS 1444.

BE 3323 INTRODUCTION TO BIOPHOTONICS (3-0) Introduction to properties of light, light-cell/tissue interactions, optical techniques, and optical instrumentation in the context of biophotonic medical applications. Topics that will be covered include fundamental properties of optical wave fields, basic properties and characterization of laser sources and detectors used in modern biomedicine, interferometery, linear and nonlinear light-tissue interactions exploited for biomedical imaging and sensing applications, and spectroscopy. Prerequisite: BIOL 1442, MAE 3319 (or EE 3317), MATH 3319, and PHYS 1444.

BE 3325 FLUORESCENCE MICROSCOPY (3-0) Introduction to the anatomy of fluorescence microscopy and the physical principles of its operation; confocal and multi-photon microscopy; molecular imaging applications based on Forster Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Recovery After Photobleaching (FRAP) and Total Internal Reflection Fluorescence (TIRF) Microscopy. Prerequisite: BIOL 1442, MAE 3319 (or EE 3317), MATH 3319, and PHYS 1444.

BE 3327 TISSUE OPTICS (3-0) Introduction to the science and technology behind tissue optical imaging systems and their design requirements for different clinical applications; diffuse optical tomography; fluorescence tomography; bioluminescence tomography; multi-modality imaging. Prerequisite: BIOL 1442, MAE 3319 (or EE 3317), MATH 3319, and PHYS 1444.

BE 3344 BIOINSTRUMENTATION (3-0) Fundamental principles of bioinstrumentation, including operational amplifiers and instrumentation amplifiers; measurements of biopotentials; signals and noise in biological systems; mechanical transducers; resistive, inductive, capacitive transducers; measurement of temperature, blood pressure and flow; electrical safety. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, and PHYS 1444.

BE 3346 MEDICAL IMAGING (3-0) This course introduces basic medical imaging modalities, including X-ray Computed Tomography (CT), Nuclear Medicine Imaging (PET and SPECT), Magnetic Resonance Imaging (MRI), and image-guided interventions. Through this course, the students will learn fundamental knowledge on how medical images are obtained and how they can be used for diagnosis, therapy, and surgery. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, and PHYS 1444.

BE 3352 DIGITAL PROCESSING OF BIOLOGICAL SIGNALS (3-0) Fundamental techniques for extraction of useful information from signals acquired from biological systems. Topics include time and frequency domain analysis, cross correlation, spectrum analysis, and convolution. Design of finite impulse response (FIR) and infinite impulse response (IIR) filters for processing biological signals are described. Examples include cardiac, respiratory, and biomechanical movements. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, PHYS 1444

BE 3364 TISSUE ENGINEERING (3-0) Fundamentals of cell/extracellular matrix interactions in terms of cell spreading, migration, proliferation and function; soft and hard tissue wound healing and nerve regeneration; polymer scaffolding materials and fabrication methods; cell-polymer interactions; in vitro and in vivo tissue culture and organ replacement. Prerequisite: BIOL 1442, CHEM 4311 (or concurrent enrollment), MATH 3319, and PHYS 1444.

BE 3372 DRUG DELIVERY (3-0) This class focuses on the development, design, and application of controlled and targeted drug delivery systems including transdermal, inhalation, drug eluting stents, stimulated-drug, as well as microparticles and nanoparticles for controlled drug delivery. Principles of drug delivery, targeting, modification, distribution and diffusion will be discussed. Prerequisite: BE 3380, BIOL 1442, CHEM 4311 (or concurrent enrollment), and MATH 3319.

BE 3380 HUMAN PHYSIOLOGY IN BE (3-0) An introduction to human physiology emphasizing biomedical engineering related topics. The course focuses on understanding basic function with the relationships on the cellular as well as organ level in both healthy and diseased states. Prerequisite: BIOL 1442, CHEM 2181, CHEM 2321, MATH 3319, and PHYS 1444.

BE 4000 UNDERGRADUATE RESEARCH (0-0) Senior level undergraduate research. Prerequisite: Departmental good standing and permission of instructor. May be taken a maximum of 3 times.

BE 4191 DIRECTED RESEARCH IN BIOENGINEERING (0-1) Student participates in a research project under the individual instruction of a faculty supervisor.

BE 4291 DIRECTED RESEARCH IN BIOENGINEERING (0-2) Student participates in a research project under the individual instruction of a faculty supervisor.

BE 4325 FUNDAMENTALS OF BIOENGINEERING (3-0) Topics cover fundamentals of biosensors, bio-signal processing, and bioinstrumentation. An introduction to various imaging modalities such as ultrasound, magnetic resonance, optical tomography, and x-ray radiography is also presented. Other bioengineering topics may be included as time allows or as is appropriate. Prerequisite: 90 or more hours (senior) standing in an engineering or science discipline or instructor's consent.

BE 4329 NEURAL ENGINEERING (3-0) This course consists of both lecture/discussion and laboratory. Lecture topics include central and peripheral nervous system injury and regeneration, brain/machine interfacing, primary culture of neural cells, neuroinflammatory and neurodegenerative disease. Laboratories include embryonic and neonatal rat derived neuronal culturing, immunostaining and quantitative analysis. Prerequisites: BIOL 3301, CSE 1301, CHEM 1442, CHEM 2322, MATH 3319 or consent of the instructor.

BE 4330 MEDICAL IMAGE PROCESSING (3-0) Principles and computational methods in digitally processing medical images are presented. Topics include image reconstruction, two and three dimensional visualization, image registration, quantitative image analysis, image enhancement, and statistical processing methods including Monte Carlo methods. Prerequisite: BE 3352, BE 3380, EE 3317 (or MAE 3319), MATH 3319, and PHYS 1444.

BE 4331 POLYMERS IN BIOMEDICAL ENGINEERING (3-0) This is a foundation course in polymeric biomaterial design, synthesis, characteriztion, and processing. The topics include design, surface-engineering, functionalization, characterization, as well as micro- and nano-fabrication of polymeric biomaterials. The biomedical applications of the polymeric biomaterials and their interaction with cell/tissue is discussed. Prerequisite: BIOL 1442, CHEM 2181, CHEM 2321, CHEM 4311 (or concurrent enrollment), MATH 3319, and PHYS 1444.

BE 4333 NANOBIOMATERIALS (3-0) Synthesis, fabrication, characterization, and biomedical applications of nanobiomaterials. Topics include synthetic nanobiomaterials, biological nanobiomaterials (DNA nanomaterials, protein and peptide nanomaterials, etc.), biofunctionalization of nanobiomaterials, and use of nanobiomaterials in tissue engineering, drug delivery, gene delivery. Prerequisite: BIOL 1442, CHEM 2181, CHEM 2321, CHEM 4311 (or concurrent enrollment), MATH 3319, and PHYS 1444.

BE 4337 TRANSPORT PHENOMENA IN BIOMEDICAL ENGINEERING (3-0) Principles of momentum, mass and heat transfer; description of blood flow, trans-capillary, interstitial, lymphatic fluid transport and pulmonary gas exchange. Applications in the design of blood oxygenator, dialysis devices, and strategies in drug delivery, hyperthermia treatment. Prerequisite: BE 3310, BE 3320, completed or concurrent BE 3380, BIOL 1442, EE 3317 (or MAE 3317), MATH 3319, PHYS 1444

BE 4345 BIOIMAGING LABORATORY (0-3) This laboratory course focuses on the use of microscopy in the life sciences, ranging from the principles of optics to the use of specialized microscopic techniques to investigate the structure and behavior of various types of cells. Students learn to use both phase and fluorescence microscopy and capture digital stills and movies with both. Students will learn how to fix and stain cells for greater exposure fo the cell details. Course will include taking and analyzing images using transmission electron microscopes and scanning electron microscopes. Prerequisite: BIOL 1442, BIOL 3301, MAE 3319 (or EE 3317), MATH 3319, PHYS 1444

BE 4350 SENIOR DESIGN PROJECT I (3-0) First of two courses in design of biomedical systems and processes. Major design project in biomedical engineering, incorporating engineering standards and realistic design constraints. This course prepares students through a major design experience incorporating engineering principles and realistic constraints that include most of the following considerations: economic, environmental, sustainability, manufacturability, ethical, health and safety, and social consideration. Prerequisite: Instructor permission required.

BE 4355 SENIOR DESIGN PROJECT II (3-0) Second of two courses in design of biomedical systems and processes. Major design project in biomedical engineering, incorporating engineering standards and realistic design constraints. This course prepares students through a major design experience incorporating engineering principles and realistic constraints that include most of the following considerations: economic, environmental, sustainability, manufacturability, ethical, health and safety, and social considerations. Prerequisite: BE 4350.

BE 4360 FUNDAMENTALS OF ULTRASOUND IN BIOENGINEERING (3-0) This course instructs the students in the physics of ultrasound transducers, their operation, and their biomedical applications. The material includes modeling of the interaction of acoustic waves with various types of tissue and cells. Mathematical methods for analyzing the reflected and refracted waves as well as constructing images from the waves will be covered. Prerequisite: BE 3380, MAE 3319 (or EE 3317), MATH 3319, PHYS 1444.

BE 4364 TISSUE ENGINEERING LECTURE (3-0) Fundamentals of cell/extracellular matrix interactions in terms of cell spreading, migration, proliferation and function; soft and hard tissue wound healing and nerve regeneration; polymer scaffolding materials and fabrication methods; cell-polymer interactions; in vitro and in vivo tissue culture and organ replacement. Prerequisite: CHEM 2181, CHEM 2321, MATH 3319, PHYS 1444.

BE 4365 TISSUE ENGINEERING LABORATORY (0-3) Each student will be given the opportunity to perform the techniques commonly used in tissue engineering and biomaterial research. These techniques are culture media preparation, cell culture/subculture, degradable scaffold preparation, scaffold modification, histological sections and staining, and cell imaging analyses. Prerequisite: BE 3380, BE 4364.

BE 4366 PROCESS CONTROL IN BIOTECHNOLOGY (2-3) Principles and methods and measurement, data acquisition, and analysis. Application of control theory in biological systems and in biotechnology processes; control of pressure, flow, tempterature, and pH. Prerequisite: BE 3380, EE 3317 (or MAE 3319), MATH 3319, PHYS 1444.

BE 4373 DRUG DELIVERY LABORATORY (3-0) This class will provide students with hands-on experience for developing drug delivery systems such as microparticles and nanoparticles that deliver pharmaceutical agents to treat various diseases. The emphasis is on understanding the principles of pharmacokinetics and drug deilvery systems to improve the clinical efficacy and reduce side effects. Prerequisite: BE 3380, CHEM 2182, CHEM 2321, concurrent or completed CHEM 4311, MATH 3319, PHYS 1444.

BE 4382 LABORATORY PRINCIPLES (0-3) Introduction to fundamental biomedical engineering laboratory procedures including human studies and animal surgery; includes clinical laboratory projects, data collection, analysis, and interpretation. Prerequisite: BE 3320, BE 3380, EE 3317 (or MAE 3319), MATH 3319, PHYS 1444.

BE 4391 DIRECTED RESEARCH IN BIOENGINEERING (3-0) Student participates in a research project under the individual instruction of a faculty supervisor.

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